I can run 6 RO clients on my Phenom II 6-core processor clocked at 3.2ghz.
I've got 16GB of ram, with 12GB available for programs (The other 4 a RAMdrive that I use for windows temp file space, because I kept having problems with several non-RO related programs creating large temporary files in the windows temp locations, such that they'd fill up the harddrive (a small SSD) - and windows doesn't deal gracefully with running out of hdd space. So i directed the temp files to the RAM drive. I also use it for repacking GRFs, since it's faster, but that's sort of overkill, since I already have a lightning fast solid state drive).
CPU temp is around 60 C Hotter than i'd like, for sure, but it's rock-solid stable, and within spec (barely). GPU is around the same temp, well within spec as well.
Edited by DrAzzy, 01 January 2013 - 02:42 PM.