Hiria's Tear is a special item... you need to do several quests to get it.
So it should be worth it.
But since the new accessoires are out, Hiria's Tear is not that worth it anymore.
Of course it is still usefull for the charm set... but the difference of two pieces Drifter Acc with Hiria's Tear to the full Drifter Set is only 11 charm.
For any other stat Hiria's tear is not usefull anymore.
You get 119 con when you use the full Vagabond set (three pieces vagabound acc, each 35 con and 14 con set bonus)... but only 110 con when you use two pieces vagabond set and Hiria's tear.
In my opinion a accessoires combination with Hiria's Tear should be ALWAYS better than any other combination of accessoires.
1. because the quests are hard and should be worth doing it
2. because of the storyline of the game... this should be the best accessoires that could be earned.